I am interested in the basic principles of large-scale brain dynamics, how these arise from (and reshape) cortical architectures, and how they underpin cognitive operations, such as perception, inference and motor control.
As a psychiatrist, I also hope to contribute to our understanding of major mental illnesses such as mood disorders, schizophrenia, autism and dementia. These contribute strongly to the burden of illness in all societies and cause significant distress to those affected.
I believe advancing our understanding of these disorders requires that we employ - and further advance - cutting edge neuroscience techniques. This is why we focus on these techniques in our group, as well as their applications.
M, Roberts G, ..., Mitchell PB (2016) Network dysfunction of emotional and cognitive
processes in those at genetic risk of bipolar disorder. Brain 138: 3427-3439.
- Hyett MP, Breakspear M, Friston KJ, Guo, CC, Parker G (2015). Disrupted effective connectivity of cortical systems supporting attention and interoception in melancholia. JAMA Psychiatry 72: 350-358.
- Iyer KK,
Roberts JA, ... ,
Vanhatalo S, Breakspear M (2015) Cortical burst dynamics predict
clinical outcome early in extremely preterm infants. Brain doi:10.1093/brain/awv129.
- Roberts G/Perry A, Lord A, ..., Mitchell PB, Breakspear M (2016). Structural dysconnectivity of key cognitive and emotional hubs in young people at high genetic risk for bipolar disorder. Molecular Psychiatry. doi: 10.1038/mp.2016.216.
- Zalesky A, Fornito A, Cocci L, Gollo LL, Breakspear M (2014) Time-resolved resting-state brain networks. PNAS doi/10.1073/pnas.140018111
Presenting our work at the The Institut de Neurosciences des Systèmes (Marseilles) Surfing at the "Maroubra Campus"
(thank you to Vik Jirsa and Patrick Chauvel)