I am currently involved in research using deformable active appearance models to assess psychomotor disturbance and emotional expression in individuals. The intention of this research is to provide an automated and clinically applicable means of measuring aberrant facial expressions in depressive disorders. It is hoped that the development and application of these models may aid in the objective index of disease expression, course and recovery that are currently limited by subjective biases.
I am also involved in various projects that utilise fMRI. These include studies into functional and structural change within an aging population, specifically the validity of clinically diagnosed subtypes of Mild Cognitive Impairment as predictors of early dementia and Alzheimer’s disease.
Additional neuroimaging projects explore the neurobiological expression of melancholic depression and the neural correlates of decision making.